They can give you tips on how to manage any side effects that may be concerning or bothersome. These lists do not include all possible side effects.įor more information about the possible side effects of Xiaflex, talk with your doctor or pharmacist. The following lists contain some of the key side effects that may occur while taking Xiaflex. Xiaflex can cause mild or serious side effects. And they tend to cost less than the parent brand-name medication. A biosimilar medication is a drug that’s similar to a brand-name biologic drug (the parent drug) and is approved for the same use.īiosimilars are considered just as safe and effective as their parent drug. It’s not possible to copy these drugs exactly. It’s not currently available in a biosimilar form.īiologic drugs are made from living cells. Xiaflex is a biologic medication, which is also called a biologic. To learn more about saving money on prescriptions, see this article. You can also visit the program website for the condition the drug is treating: Dupuytren’s contracture or Peyronie’s disease. For more information and to find out if you’re eligible for support, call 877-XIAFLEX (87). If you need financial support to pay for Xiaflex, or if you need help understanding your insurance coverage, help is available. If you’re not sure if you’ll need to get prior authorization for Xiaflex, contact your insurance company. The insurance company will review the prior authorization request and decide if the drug will be covered. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. It will also depend on the cost of the visit to your healthcare professional to receive doses of Xiaflex.īefore approving coverage for Xiaflex, your insurance company may require you to get prior authorization. The actual price you’ll pay depends on your insurance plan, your location, and the pharmacy you use. Effectivenessįor information about the effectiveness of Xiaflex, see the “ Xiaflex uses” section below.Īs with all medications, the cost of Xiaflex injections can vary. For Peyronie’s disease, they’ll inject Xiaflex into the plaque in your penis. Your doctor will use the powder to make a liquid solution of Xiaflex that’s given by injection.įor Dupuytren’s contracture, your doctor will inject Xiaflex into the cord in your hand. Xiaflex comes as a powder inside single-use vials. Collagenase breaks down collagen, which is the main protein that makes up connective tissue and scar tissue. The active drug is an enzyme called collagenase that’s extracted from Clostridium histolyticum bacteria. Xiaflex contains the active drug collagenase clostridium histolyticum. Use of the term “male” in this article refers to sex assigned at birth. Xiaflex is approved to treat Dupuytren’s contracture where a cord can be felt. Over time, cords of connective tissue can develop that pull your finger in toward your palm and prevent you from straightening it. It also treats males that have a curve in the penis of 30 degrees or more when starting treatment.ĭupuytren’s contracture is a condition in which the connective tissue under the skin in your palms and fingers thickens and tightens. Xiaflex is approved to treat Peyronie’s disease in males* who have a plaque that can be felt. These plaques cause your penis to curve painfully, especially when erect. With Peyronie’s disease, plaques (fibrous scar tissue) develop under the skin of your penis. It’s FDA-approved to treat the following conditions in adults: Xiaflex is a brand-name prescription medication.
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